Summary
Overview
Work History
Education
Skills
Affiliations
Publications
References
Training
Timeline
Generic

Cynthia Mubanga

Lusaka,09

Summary

With 14 years of diverse experience in clinical and research laboratory environments, bringing a robust skill set honed through collaboration with government health ministries and non-profit organizations. Proficient across various laboratory assays encompassing microbiology, immunology, and molecular biology, with expertise leaning towards immunological responses to vaccines. Currently in the final year of PhD in Medical Microbiology and Immunology studies with a research focus on systemic memory responses to a candidate vaccine against Enterotoxigenic E.coli in Zambian children aged 6-23 months.

In addition to research pursuits, contributed to microbiology initiatives and provided mentorship in both microbiology and antimicrobial resistance (AMR) monitoring within clinical settings. Recognized for organizational skills and reliability, excelling in managing multiple priorities while maintaining a positive outlook. Committed to team success, I eagerly embrace additional responsibilities to advance collective objectives.

Overview

15
15
years of professional experience

Work History

Research Fello

Center for Infectious Disease Research in Zambia
01.2018 - Current
  • Working on Ph.D project to access systemic memory responses to an oral vaccine against Enterotoxigenic E.coli
  • Working as a laboratory scientist on various other projects as assigned by the chief scientific officer and performing various biomedical assays such as cell culture, ELISAs, PCR assays, bactericidal assays, PBMC isolations and ELISPOT assays.
  • Participating in research proposal development, laboratory testing of project samples, manuscript, and grant writing
  • Working as study coordinator for Noro and rotavirus surveillance study at Arthur Davison Children Hospital (ADCH) site conducted with support from CDC and in collaboration with the Tropical Diseases Research Centre (TDRC) as well as conducting sample testing and data management
  • Participating in the implementation of the national multi-pathogen diagnostic program, strengthening microbiology and AMR efforts in public laboratories through capacity building and mentorship
  • Key achievements: Successfully set up vaccine immunogenicity assays after training in India and Sweden
  • Leading laboratory work in the Phase 1 trial which is assessing the safety and immunogenicity of a vaccine against enterotoxigenic E. Coli (ETVAX)
  • Successfully wrote and submitted a grant proposal to BACTIVAC
  • Helping public laboratories strengthen their AMR monitoring capacities.
  • Used critical thinking to break down problems, evaluate solutions and make decisions.
  • Demonstrated strong organizational and time management skills while managing multiple projects.
  • Skilled at working independently and collaboratively in a team environment.
  • Authored professional scientific papers for publishing in peer-reviewed journals.

Biomedical Scientist

University Teaching Hospital Laboratories (Virology)
01.2009 - 01.2018
  • Performed diagnostic testing of clinical samples, data management, and leading quality management system initiatives
  • Performed HIV viral load testing, flow cytometry, various ELISAs, microbiology techniques including bacterial cultures and influenza and polio virus-cell cultures, real-time and conventional PCR
  • Participated in the 2013/2014 Zambia Demographic and Health Survey and as supervisor for field lab staff and performed sample testing for the National yellow fever risk assessment
  • Gained extensive knowledge in data entry, analysis and reporting.
  • Key achievements: Spearheaded the accreditation of the virology laboratory to ISO15189.
  • Mentored junior staff members to foster professional growth, skill development, and career advancement opportunities within the organization.
  • Used strong analytical and problem-solving skills to develop effective solutions for challenging situations.
  • Recorded and analyzed data to produce reports of results.
  • Actively participated in industry conferences or workshops to stay current on trends, innovations, or best practices relevant to laboratory operations or management responsibilities.
  • Provided technical guidance and training to laboratory staff as laboratory supervisor

Research Scientist

Tropical Gastroenterology and Nutrition Research Group (TROPGAN)
01.2009 - 04.2009
  • Performed laboratory PCR testing of project samples
  • Participated in research projects by designing and executing experiments.
  • Conducted literature reviews and compiled relevant information, supporting the development of new hypotheses.
  • Worked flexible hours across night, weekend, and holiday shifts.
  • Participated in lab meetings, journal clubs and project presentations.

Education

Doctor of Philosophy in Medical Microbiology and Immunology - Medical Microbiology And Immunology

Stellenbosch University
South Africa

Master of Science in Infectious Diseases -

University of London
London, United Kingdom
01.2015

Bachelor of Science – Biomedical Sciences -

The University of Zambia
Lusaka, Zambia
01.2009

Skills

  • Laboratory management
  • Project coordination
  • Training and mentoring
  • Laboratory diagnostic assays (immunological, microbiological, and molecular)
  • Research design, implementation and report writing
  • Proficient in Microsoft Word, PowerPoint, and Excel
  • Grant Writing
  • Analytical Thinking

Affiliations

  • African Society for Laboratory Medicine (ASLM)
  • Biomedical Society of Zambia (BMSZ)
  • American Society for Microbiology (ASM)
  • Bactivac Network
  • Immunology Society of Zambia (ISZ)

Publications

  • Seroepidemiology of hepatitis E virus infection in an urban population in Zambia: strong association with HIV and environmental enteropathy, Journal of Infectious Diseases, 2013, Jacobs C, Chiluba C, Phiri C, Lisulo M.M, Chamba M, et al, 209, 5, 652-657
  • Impact Of Rotavirus Vaccination On Diarrheal Hospitalisations In Children Aged Under Five In Lusaka, Zambia, Journal of clinical infectious Diseases, 2016, Mpabalawani E.M, Simwaka C.J, Mwenda J.M, Mubanga C.P, Monze M, et al, 62, suppl2, S183
  • Seroprevalence of arthropod-borne viral infections among Lukanga swamp residents in Zambia, PLOS ONE, 2020, Chisenga CC, Bosomprah S, Musukuma K, Mubanga C, Chilyabanyama ON, et al., 15, 7
  • In-vitro inhibitory effect of maternal breastmilk components on rotavirus vaccine replication and association with infant seroconversion to live oral rotavirus vaccine, PLOS ONE, 2020, Kazimbaya KM, Chisenga CC, Simuyandi M, Phiri CM, Laban NM, et al., 15, 11
  • Effect of HIV status and retinol on immunogenicity to oral cholera vaccine in adult population living in an endemic area of Lukanga Swamps, Zambia, PLOS ONE, 2021, Charlie Chaluma Luchen, John Mwaba, Harriet Ng’ombe, Peter Ibukun Oluwa Alabi, Michelo Simuyandi, Obvious N. Chilyabanyama, Luiza Miyanda Hatyoka, Cynthia Mubanga et al., 16, 12
  • Immunogenicity and waning immunity from the oral cholera vaccine (Shanchol) in adults residing in Lukanga Swamps of Zambia, PLOS ONE, 2022, Harriet Ngombe, Michelo Simuyandi, John Mwaba, Charlie Chaluma Luchen, Peter Alabi, Obvious Nchimunya Chilyabanyama, Cynthia Mubanga et al., 17, 1
  • Use of an ETEC ProteomeMicroarray to Evaluate Cross-Reactivity of ETVAX Vaccine-Induced IgG Antibodies in Zambian Children, Vaccines, 2023, Cynthia Mubanga, Michelo Simuyandi, Kapambwe Mwape, Kennedy Chibesa, Caroline Chisenga, Obvious Nchimunya Chilyabanyama, Arlo Randall, Xiaowu Liang, Richard H. Glashoff and Roma Chilengi, 2023, 11, 939
  • Evaluation of ROTARIX Booster Dose Vaccination at 9 Months for Safety and Enhanced Anti-Rotavirus Immunity in Zambian Children: A Randomised Controlled Trial, Vaccines, 2023, Laban NM, Bosomprah S, Simuyandi M, Chibuye M, Chauwa A, Chirwa-Chobe M, Sukwa N, Chipeta C, Velu R, Njekwa K, Mubanga C, Mwape I, Goodier MR, Chilengi R., 11, 2, 346
  • Maternal and Infant Histo-Blood Group Antigen (HBGA) Profiles and Their Influence on Oral Rotavirus Vaccine (RotarixTM) Immunogenicity among Infants in Zambia, Vaccines, 2023, Chauwa A, Bosomprah S, Laban NM, Phiri B, Chibuye M, Chilyabanyama ON, Munsaka S, Simuyandi M, Mwape I, Mubanga C, Chobe MC, Chisenga C, Chilengi R., 11, 8, 1303
  • Prevalence of Diarrhoeagenic Escherichia coli among Children Aged between 0–36 Months in Peri-Urban Areas of Lusaka, Microorganisms, 2023, Mwape K.; Bosomprah S.; Chibesa K.; Silwamba S.; Luchen, C.C.; Sukwa, N.; Mubanga, C.; Phiri, B.; Chibuye, M.; Liswaniso, F.; et al., 11, 11, 2790
  • Application of a Novel Proteomic Microarray Reveals High Exposure to Diarrhoeagenic Escherichia coli among Children in Zambia Participating in a Phase I Clinical Trial, Microorganisms, 2024, Mwape K, Mubanga C, Chilyabanyama ON, Chibesa K, Chisenga CC, Silwamba S, Randall A, Liang X, Barnard TG, Simuyandi M, et al., 12, 3, 420
  • Safety, tolerability, and immunogenicity of an oral inactivated ETEC vaccine (ETVAX) with dmLT adjuvant in healthy adults and children in Zambia: An age descending randomised, placebo-controlled trial, Vaccine, 2023, Nsofwa Sukwa, Cynthia Mubanga, Luiza M. Hatyoka, Obvious N. Chilyabanyama, Mwelwa Chibuye, Samson Mundia, Masiliso Munyinda, Ethel Kamuti, Muyunda Siyambango, Sharif Badiozzaman, Samuel Bosomprah, Nils Carlin, Joanna Kaim, Björn Sjöstrand, Michelo Simuyandi, Roma Chilengi, Ann-Mari Svennerholm, 41, 46, 6884-6894
  • The 2022 Vaccines Against Shigella and Enterotoxigenic Escherichia coli (VASE) Conference: Summary of abstract-based presentations, Vaccine, 2023, Banerjee S, Barry EM, Baqar S, Louis Bourgeois A, Campo JJ, Choy RKM, Chakraborty S, Clifford A, Deal C, Estrada M, Fleckenstein J, Hasso-Agopsowicz M, Hausdorff W, Khalil I, Maier N, Mubanga C, Platts-Mills JA, Porter C, Qadri F, Simuyandi M, Walker R, White JA, Epub ahead of print

References

  • Prof. Roma Chilengi, Director General, Zambia National Public Health Institute, Lusaka, Zambia, chilengir@yahoo.com, +26073724935
  • Dr. Mwaka Monze, Unit Head, Virology Laboratory, University Teaching Hospital, Lusaka, Zambia, mwakamonze@hotmail.com, +260977793654
  • Dr. Nicksy Gumede, WHO Afro Regional Virologist, Brazaville, Congo, gumedemoeletsih@who.int, +27834922794

Training

  • October 2023, 4th Annual Bactivac meeting, Poster Presenter, Cross-reactivity of the ETVAX vaccine-induced IgG antibodies to non-vaccine ETEC antigens and Diarrhoeagenic Escherichia coli specific antigens: A microarray analysis
  • October 2022, Zambia National Health Research Conference, Lusaka, Zambia, Oral Presenter, Use of an ETEC proteome microarray to evaluate cross-reactivity of ETVAX vaccine induced IgG antibodies in Zambian children
  • November 2022, Vaccines against Shigella and ETEC (VASE) Conference, Washington DC, USA, Oral Presenter, Cross-reactivity of the ETVAX vaccine-induced IgG antibodies to non-vaccine ETEC antigens and Diarrhoeagenic Escherichia coli specific antigens: A microarray analysis
  • Good Clinical Practice (GCP), RCR, January 2022
  • African Advanced Vaccinology course, September 2021, Wits University
  • GCP, RCR, November 2018
  • Quality Management systems (QMS), September 2016, MOH
  • Infectious substance shippers training, May 2016, WHO
  • African Regional Biosafety workshop, October 2015, CDC
  • Surveillance of vaccine-preventable diseases, August 2015, WHO
  • Integrated Polio Lab database, May 2015, WHO
  • Estimating HIV-1 incidence using the LAg-Avidity EIA, September 2014, CDC
  • Polio/ enterovirus isolation and intratypic differentiation by rRT-PCR, June 2014, WHO
  • Influenza virus isolation, November 2013, WHO
  • Early infant diagnosis for HIV and HIV viral load testing using Cobas Ampliprep/Taqman 48, May 2013, Roche Diagnostics
  • Supply chain management system, 2011, MOH

Timeline

Research Fello

Center for Infectious Disease Research in Zambia
01.2018 - Current

Biomedical Scientist

University Teaching Hospital Laboratories (Virology)
01.2009 - 01.2018

Research Scientist

Tropical Gastroenterology and Nutrition Research Group (TROPGAN)
01.2009 - 04.2009

Doctor of Philosophy in Medical Microbiology and Immunology - Medical Microbiology And Immunology

Stellenbosch University

Master of Science in Infectious Diseases -

University of London

Bachelor of Science – Biomedical Sciences -

The University of Zambia
Cynthia Mubanga